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Health Resources and Services Administration
The purpose of this program is to supplement formula-based funding provided through the HIV Care Grant Program – RWHAP Part B States/Territories Formula and AIDS Drug Assistance Program (ADAP) Formula and ADAP Supplemental Awards Notice of Funding Opportunity.
Health Resources and Services Administration
The purpose of this cooperative agreement is to provide tools, training and technical assistance (TA) to RWHAP Parts A and B recipients and their planning bodies to support integrated HIV prevention and care planning, maximizing resources and stregthening the system of HIV care and treatment.
Health Resources and Services Administration
The purpose of the program is to strengthen the capacity of community-based organizations to improve health outcomes and reduce HIV transmission, especially for people not yet in regular HIV care. The activities fall under two categories: HIV Care Innovation and Infrastructure Development.
Health Resources and Services Administration
The purpose of this program is to provide funding to states and territories to develop and/or enhance access to a comprehensive system of high-quality HIV care and treatment for low-income people with HIV.
Health Resources and Services Administration
The purpose of this program is to provide funding to states/territories to prevent, reduce, or eliminate ADAP waiting lists or to address other ADAP shortfalls.
Centers for Disease Control - NCEZID
The CDC announces the availability of FY 2027 funds for a cooperative agreement to continue enhanced national surveillance for human prion diseases, also known as transmissible spongiform encephalopathies (TSEs), in the United States. The purpose is to continue an active surveillance program to help confirm suspected and clinically diagnosed cases of human prion disease and to monitor the occurrence of potentially emerging human prion diseases in the United States. Outcomes are enhanced national surveillance for always fatal human prion diseases through improved diagnoses and continued monitoring for emerging or new prion diseases in the United States. These outcomes are accomplished through the funding of a specialized center to conduct state-of-the-art diagnostic techniques. Prion diseases can only be confirmed through brain tissue analyses, and many facilities lack the expertise and/or the willingness, due to infection control concerns, to handle and accurately diagnose specimens from suspected cases. Since 1997, the Centers for Disease Control and Prevention (CDC) has funded a center to provide prion disease diagnostic services, which has allowed for disease confirmation, evaluation of disease trends over time, and identification of disease subtypes. Data have been shared with CDC experts who partner with center staff, providing guidance and epidemiological knowledge. This collaboration has contributed to accurate national surveillance findings and helped to provide confidence that novel prion diseases, such as a human form of the animal prion disease, chronic wasting disease, have not been occurring in the country.
Centers for Disease Control and Prevention - ERA
The Centers for Disease Control and Prevention's (CDC) National Center for Injury Prevention and Control (NCIPC) is soliciting investigator-initiated gold standard research proposals to rigorously evaluate programs and policies for their impact on primary prevention of child sexual abuse (CSA) or problematic sexual behavior (PSB) among youth. For the purposes of this NOFO: CSA is defined as sexual victimization during childhood (younger than 18 years of age) perpetrated by an adult. PSB is defined as sexual behaviors among children (younger than 18 years of age) that are not developmentally appropriate and have the potential to cause harm to the child or children involved (including behaviors that are unintentionally harmful or inappropriate as well as behaviors intended to cause harm). Research funded under this announcement will strengthen the evidence base for primary prevention of CSA and PSB. Applicants must propose to rigorously evaluate a program or policy for primary prevention of CSA or PSB that addresses one of the following three research priorities: Programs or policies focused on primary prevention of CSA or PSB in digital spaces (e.g., downloading or possession of illegal images of children, nonconsensual image sharing, use of artificial intelligence to create fake explicit images of children); Programs or policies addressing the use of digital spaces for commercial sexual exploitation of children (CSEC) or sex trafficking (e.g., online recruitment of minors for sexual content creation, online advertisements soliciting minors for commercial sex acts, using technology to facilitate in-person meetings with minors for the purpose of sex); Organizational policy approaches focused on primary prevention of CSA or PSB in youth-serving organizations (e.g., community centers, youth development organizations, juvenile residential care facilities, faith-based organizations, group foster care).
Centers for Disease Control and Prevention - ERA
The Centers for Disease Control and Prevention's (CDC) National Center for Injury Prevention and Control (NCIPC) seeks investigator-initiated research proposals to evaluate primary prevention-focused approaches to reduce suicide and interpersonal violence among youth and young adults (ages 10 to 24 years). This NOFO will support the evaluation of existing primary prevention approaches (i.e., approaches that are already developed and implemented or have been shown to be ready for implementation) that have not yet undergone rigorous evaluation. For this announcement, "approaches" can include programs, policies, or practices. Applicants can propose to evaluate approaches that: Reduce suicide-related outcomes, enhancing social connectedness and social cohesion at the community level Reduce or mitigate the impact of unhealthy behaviors or experiences in online spaces on suicide-related outcomes Evaluate approaches to reduce the incidence and/or harm caused by technology-facilitated forms of interpersonal violence
Centers for Disease Control - NCHHSTP
In alignment with CDC's viral hepatitis strategic goals and current epidemiology, this Notice of Funding Opportunity (NOFO) will address the need for increasing awareness of viral hepatitis prevention, testing, and treatment options among populations disproportionately affected by hepatitis B and/or hepatitis C virus infections. The priority populations' needs will also be addressed by increasing healthcare professionals' competence in the evaluation and treatment of hepatitis B and/or hepatitis C virus infection. The outcomes of this NOFO will be achieved through two separate components. An organization may apply for one component or both components by submitting two separate applications, one for Part A and one for Part B. Part A: Community Education, Awareness, and Capacity Building, and Part B: Professional Education and Training. Strategies and activities conducted under each part may contribute to more people with hepatitis B and hepatitis C able to make informed health decisions and obtain proper care and treatment which can lead to decreased morbidity and mortality from hepatitis B and hepatitis C. Part A strategies and activities focus on 1) leading, maintaining, and growing an existing coalition of public and private organizations serving populations disproportionately affected by hepatitis B and/or hepatitis C, 2) providing technical assistance and training to coalition members to deliver hepatitis B and/or hepatitis C educational outreach to disproportionately affected populations, and 3) building capacity of coalition members to conduct hepatitis B and/or hepatitis C virus infection testing and linkage to treatment in settings serving disproportionately affected populations. Short-term outcomes include increasing capacity of the coalition to expand services to a larger number of populations disproportionately affected by hepatitis B and hepatitis C, increasing capacity of coalition members to deliver hepatitis B and/or hepatitis C educational outreach to disproportionately affected populations, and increasing testing for hepatitis B and/or hepatitis C virus infection among disproportionately affected populations. Part B strategies and activities focus on 1) providing free comprehensive web-based, accurate, on-demand resources and trainings for healthcare professionals for hepatitis B and hepatitis C, and associated continuing education credits, and 2) actively marketing and promoting training and resources.
Centers for Disease Control and Prevention - ERA
The Centers for Disease Control and Prevention’s (CDC) National Center for Injury Prevention and Control (NCIPC or the Injury Center) is soliciting investigator-initiated research to rigorously evaluate the effectiveness of innovative and promising approaches to prevent all forms of firearm-related injuries, deaths, violence, or crime without infringing on the rights of legal firearm owners. For this announcement such forms include: Mass shooting incidents, Defensive gun use incidents, Firearm-related homicides and assaults, Firearm-related suicides and self-harm, Unintentional firearm deaths and injuries, Firearm-related crime. This NOFO offers Funding Option A or B to address the research objective. Applicants may submit a research proposal under either Funding Option A or B (not both). Funding Option A will support research projects that rely on existing data to evaluate effectiveness and that do not support implementing prevention activities. These projects will be funded up to $350,000 per year (direct and indirect costs) for a period of performance up to 2 years. Funding Option B will support research projects that require new data collection and/or implementation of prevention activities to evaluate effectiveness. These projects will be funded up to $650,000 per year (direct and indirect costs) for a period of performance up to 3 years. Investigations could, for example , conduct research to evaluate the effectiveness and/or test the effects of scaling up, expanding, or improving approaches: 1) To prevent mass shooting incidents, suicide/self-harm firearm injuries, firearm-related assaults and homicides, unintentional firearm deaths and injuries, and firearm-related crime; 2) To study defensive gun use as a strategy for prevention of injuries, deaths, and crime 3) For different population groups (e.g., children, youth, young adults, active-duty military/veterans, rural communities, tribal populations, and those at risk of harming themselves or others, including in situations of family and intimate partner violence); 4) For different settings (e.g., rural/urban, home, school, neighborhood, community, online) that can be leveraged to prevent firearm-related injuries and crime; 5) For addressing various individual, peer/family, community and societal risk and protective factors including approaches that address the community factors that contribute to firearm-related injuries, violence, deaths, and crime.
National Institutes of Health
The Tobacco Regulatory Science Program, participating NIH Institutes and Centers (ICs), and the Food and Drug Administration (FDA) Center for Tobacco Products (CTP) intend to issue a Notice of Funding Opportunity (NOFO) soliciting applications for Tobacco Centers of Regulatory Science (TCORS). The awards under this NOFO will be administered by NIH using funds made available through FDA CTP and the Family Smoking Prevention and Tobacco Control Act (P.L. 111-31) (FSPTCA). The TCORS program objective is to establish collaborative multidisciplinary research centers that will expand the scientific base informing regulation of tobacco products to protect public health and support implementation of the FSPTCA. Centers are expected to include at least three discrete hypothesis driven Research Projects with a scientific Integrative Theme. The NOFO will solicit research applications within the regulatory authority of FDA CTP on one or more of the following topics: Addiction Behavior Communications Health Effects Impact Analysis Marketing Product Composition and Design Toxicity
Health Resources and Services Administration
The Health Workforce Research Centers support research that helps decision-makers at the federal, state, and local levels understand health workforce needs.
Health Resources and Services Administration
The Children’s Hospitals Graduate Medical Education (CHGME) Payment Program funds freestanding, children's hospitals. The money helps their graduate medical education (GME) programs train resident physicians and dentists.
Health Resources and Services Administration
The purpose of the THCGME Program is to provide maintenance funding to support the training of residents in existing HRSA-supported primary care residency training programs in community-based ambulatory patient care centers. These programs will prepare residents to provide high-quality care, particularly in rural and medically vulnerable communities, and develop competencies to serve a wide range of populations and communities.
National Institutes of Health
The purpose of this forecast is to inform the research community that the NIH Common Fund, along with its partner NIH Institutes, Centers, and Offices, is planning to issue a notice of funding opportunity (NOFO) to support the continuation of the Bridge2AI program. Stage 1 of the Bridge2AI program produced unique, large-scale, valuable, and open resource, AI-ready datasets and best practices that the scientific community can adopt. The second stage of the program will foster advances on two fronts: 1) Leverage the AI-ready datasets from Stage 1 to yield products that can address biomedical and behavioral research grand challenges, accelerate the discovery of new biological theories and rules, and advance understanding of biological and behavioral mechanisms of health and disease; 2) Create networks of multidisciplinary researchers to advance the science of AI science by developing necessary metrics and a framework to for trustworthy, reproducible and explainable AI-enabled biomedical and behavioral research. This forecast is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. The NOFO will support a research initiative that will create a network of multidisciplinary Centers to advance the science of AI science. Centers will work across the evolving landscape of AI science to create a framework for trustworthy, reproducible and explainable AI-enabled biomedical and behavioral research. Center activities will include evaluation of AI models and products built through other initiatives in the program and other sources, convening expert panels and round tables, supporting pilot research activities, multidisciplinary cross-training and dissemination activities to help grow the nascent field of biomedical and behavioral research AI science. The Network of Centers will produce best practices for AI methods and trustworthy AI model building principles, frameworks to enable the evaluation of AI models and methods for reproducibility, replicability and transparency, guiding principles for agentic autonomous labs of the future, and multidisciplinary training to strengthen the American biomedical and behavioral research AI workforce. This initiative will support 3-5 Centers, and is one of twoInitiatives under the Bridge2AI program, the other of which will be supported by a research contract.
Centers for Disease Control and Prevention - ERA
CDC/ATSDR is inviting research proposals to study risk factors for Amyotrophic Lateral Sclerosis (ALS). Studies on military service, contact sports, traumatic brain injury, neuroinflammation, and infections agents and exposures are encouraged. Funding will be for four funding options: Option A - Support research with strong existing evidence such as studies on known environmental or genetic risk factors, research that improves past studies with better data, or investigations linking risk factors to ALS diagnosis and treatment; Option B - Support new and exploratory research on ALS risk factors such as studies on risk factors with little existing evidence or research using innovative methods; Option C - Understand ALS risk in affected populations, such as studies involving military veterans or investigations of ALS risk factors impacting this population; Option D - Analyze biological samples from the Guamanian ALS cluster such as investigation of disease mechanisms and environmental factors, exposure routes, genetic studies and biomarkers and how this could lead to mitigation therapeutics, diagnostics or prevention.
National Institutes of Health
The NIH Blueprint for Neuroscience Research is interested in continuing to support the B lue P rint N eurotherapeutics Network for S mall M olecules (BPN-SM)- a program designed to help investigators advance promising small-molecule therapeutics toward clinical testing. The BPN-SM program supports drug discovery and development activities in investigators’ own laboratories while also providing access to NIH-supported subject matter experts and contract research organizations (CROs) with capabilities in medicinal chemistry, pharmacokinetics, toxicology, formulation development, GMP synthesis, and Phase I clinical testing. By integrating NIH resources with industry-standard expertise, BPN-SM advances investigator-initiated drug discovery while enabling investigators to retain and strengthen their intellectual property while gaining hands-on experience in translational drug development. The overarching goal of the program is to reduce the risk of scientific and therapy development sufficiently to enable external partners to take on late-stage development and ultimately bring new therapies to patients. In addition, this BPN program is specifically focused on small molecules and excludes biologics, because development, regulatory, and manufacturing considerations for each class of therapeutics differ substantially from each other. It will use a phased cooperative agreement mechanism which will enable the program to support innovative but higher-risk projects, with decisions of continued support being contingent on demonstrated feasibility of yearly milestones. A cooperative agreement framework is proposed because several key aspects of the program will involve collaborative activities between the investigators and NIH program staff, with substantial involvement beyond the normal scope of grant stewardship. The project principal investigator(s) and NIH program staff will work jointly with NIH-supported subject matter experts to coordinate and participate in all scientific and technical management aspects of the project. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop competitive projects and establish the cross-disciplinary collaborations necessary for success.
National Institutes of Health
This initiative will provide salary and research support to advanced U.S. postdoctoral researchers and junior faculty for intensive mentored research and career development activities focused on biomedical, behavioral, and/or clinical research in low- and middle-income countries (LMICs). Proposals will leverage special opportunities not present in the U.S. and result in generalizable knowledge applicable to the health of U.S. and LMIC populations. Recipients will be required to spend significant time at the LMIC research site and receive mentoring from senior U.S. and LMIC researchers. This experience will provide recipients with a deep understanding of the local research environment and foster collaborative relationships necessary to develop competitive independent NIH research proposals. A sustained period of research career development will enable recipients to become global leaders in their fields, serve as mentors to the next generation of investigators, and strengthen international networks that support NIH research investments.
Centers for Disease Control and Prevention - ERA
The National Institute for Occupational Safety and Health (NIOSH) World Trade Center (WTC) Health Program K01 Award supports early-career investigators in developing independent research careers focused on improving the health and well-being of populations affected by the September 11, 2001, terrorist attacks (9/11). This award provides up to three years of mentored research and career development support, including at least 75 percent protected time. The program supports research that improves understanding of physical and mental health effects associated with 9/11 exposures, addresses diagnostic or treatment uncertainty, identifies emerging health concerns, examines aging among exposed populations, and informs improvements in clinical care, public health practice, and long-term health outcomes. Research that helps translate scientific findings into improved care and public health practice is encouraged. Responsive research may include epidemiologic, clinical, translational, preclinical, health services, health outcomes, diagnostic, treatment, prevention, quality-of-life, and implementation research. Generalizability to other populations is not required. The award also supports the development of the next generation of investigators needed to address health needs related to 9/11 exposure. More information, including the WTC Health Program Research Agenda and previously funded projects, is available at: https://www.cdc.gov/wtc/researchagenda.html and https://www.cdc.gov/wtc/fundingdashboard.html .